Combined ion exchange & physical entrapment virus removal mechanisms

FDA Drug Master File and USP Class VI Biological Safety that eases validation and regulatory submissions by providing vital documentation and traceability.

Viral log reduction

3M™ Zeta Plus™ VR Series filter media is a family of cellulosic depth filtration media designed to retain contaminants by both physical entrapment and ion exchange absorption.

Zeta Plus VR Series Media are composed of high-area process filter aids embedded in a cellulose fiber depth matrix. During the manufacturing process, a cationic charge modifier is chemically bound to the matrix components, forming a permanent, interconnected, rigid depth filter with positively-charged electrokinetic capture sites. The resulting porous depth filter structure is a tortuous network of absorptive flow channels capable of retaining contaminating viruses through a combination of anion exchange absorption and mechanical entrapment. Cumulative viral titer reduction may also be attainable through a staged two-step Zeta Plus system.